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Efficient genetically controlled formation of antibody to a synthetic antigen [poly(LTyr, LGlu)-poly(DLAla)- -poly(LLys)] covalently bound to a synthetic adjuvant (N-acetylmuramyl-L-alanyl-D-isoglutamine).

The synthetic polypeptide antigen poly(LTyr, LGlu)-poly(DLAl)- -poly(LLys)[T,G)-A- -L] was covalently linked to N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP), which is the minimal adjuvant-active structure that can substitute for Mycobacteria in complete Freund's adjuvant. When injected in aqueous s...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Mozes, E, Sela, M, Chedid, L
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1980
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6776530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.4933
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