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Adoptive immunotherapy combined with intratumoral TLR agonist delivery eradicates established melanoma in mice

Toll-like receptor (TLR) agonists can trigger broad inflammatory responses that elicit rapid innate immunity and promote the activities of lymphocytes, which can potentially enhance adoptive immunotherapy in the tumor-bearing setting. In the present study, we found that Polyinosinic:Polycytidylic Ac...

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Detalhes bibliográficos
Main Authors: Amos, Sally M., Pegram, Hollie J., Westwood, Jennifer A., John, Liza B., Devaud, Christel, Clarke, Chris J., Restifo, Nicholas P., Smyth, Mark J., Darcy, Phillip K., Kershaw, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499620/
https://ncbi.nlm.nih.gov/pubmed/21327636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-0984-8
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