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Toll-Like Receptor 8 Ligands Activate a Vitamin D Mediated Autophagic Response that Inhibits Human Immunodeficiency Virus Type 1

Toll-like receptors (TLR) are important in recognizing microbial pathogens and triggering host innate immune responses, including autophagy, and in the mediation of immune activation during human immunodeficiency virus type-1 (HIV) infection. We report here that TLR8 activation in human macrophages...

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Autors principals: Campbell, Grant R., Spector, Stephen A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499571/
https://ncbi.nlm.nih.gov/pubmed/23166493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003017
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