Endogenous cGMP-dependent protein kinase reverses EGF-induced MAPK/ERK signal transduction through phosphorylation of VASP at Ser239

In our previous study, we demonstrated that type II cGMP-dependent protein kinase (PKG II) was expressed at lower levels in different human cancer cell lines and that exogenous PKG II inhibited epidermal growth factor (EGF)-induced MAPK/ERK signaling. In order to investigate its functions further in...

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Main Authors: TAO, YAN, GU, YIN-JIE, CAO, ZHI-HONG, BIAN, XIU-JUAN, LAN, TING, SANG, JIAN-RONG, JIANG, LU, WANG, YING, QIAN, HAI, CHEN, YONG-CHANG
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499524/
https://ncbi.nlm.nih.gov/pubmed/23162660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2012.851
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