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Clinical Presentation of Atopic Dermatitis by Filaggrin Gene Mutation Status during the First 7 Years of Life in a Prospective Cohort Study

BACKGROUND: Filaggrin null mutations result in impaired skin barrier functions, increase the risk of early onset atopic dermatitis and lead to a more severe and chronic disease. We aimed to characterize the clinical presentation and course of atopic dermatitis associated with filaggrin mutations wit...

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Detalhes bibliográficos
Main Authors: Carson, Charlotte Giwercman, Rasmussen, Morten Arendt, Thyssen, Jacob P., Menné, Torkil, Bisgaard, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499508/
https://ncbi.nlm.nih.gov/pubmed/23166590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048678
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