Fas-deficient mice have impaired alveolar neutrophil recruitment and decreased expression of anti-KC autoantibody:KC complexes in a model of acute lung injury

BACKGROUND: Exposure to mechanical ventilation enhances lung injury in response to various stimuli, such as bacterial endotoxin (LPS). The Fas/FasL system is a receptor ligand system that has dual pro-apoptotic and pro-inflammatory functions and has been implicated in the pathogenesis of lung injury...

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Detalhes bibliográficos
Main Authors: Gil, Sucheol, Farnand, Alex W, Altemeier, William A, Gill, Sean E, Kurdowska, Anna, Krupa, Agnieszka, Florence, Jon M, Matute-Bello, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499442/
https://ncbi.nlm.nih.gov/pubmed/23043753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-91
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