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Soluble KIT correlates with clinical outcome in patients with metastatic breast cancer treated with sunitinib

BACKGROUND: Sunitinib inhibits vascular endothelial growth factor receptors (VEGFRs), platelet-derived growth factor receptors, and stem cell factor receptor (KIT). The ability of soluble (s)KIT, VEGF-A, sVEGFR-2, and sVEGFR-3 to predict clinical outcome was analyzed in 61 patients with previously t...

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Main Authors: Keyvanjah, Kiana, DePrimo, Samuel E, Harmon, Charles S, Huang, Xin, Kern, Kenneth A, Carley, William
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499375/
https://ncbi.nlm.nih.gov/pubmed/22897944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-165
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