Genome-wide aberrant DNA methylation of microRNA host genes in hepatocellular carcinoma

Mature microRNAs (miRNAs) are a class of small non-coding RNAs involved in posttranslational gene silencing. Previous studies found that downregulation of miRNAs is a common feature observed in solid tumors, including hepatocellular carcinoma (HCC). We employed a genome-wide approach to test the hyp...

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Détails bibliographiques
Auteurs principaux: Shen, Jing, Wang, Shuang, Zhang, Yu-Jing, Kappil, Maya A., Chen Wu, Hui, Kibriya, Muhammad G., Wang, Qiao, Jasmine, Farzana, Ahsan, Habibul, Lee, Po-Huang, Yu, Ming-Whei, Chen, Chien-Jen, Santella, Regina M.
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2012
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499324/
https://ncbi.nlm.nih.gov/pubmed/22976466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22140
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