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Trifunctional antibody ertumaxomab: Non-immunological effects on Her2 receptor activity and downstream signaling
Background: The trifunctional antibody ertumaxomab bivalently targets the human epidermal growth factor receptor 2 (Her2) on epithelial (tumor) cells and the T cell specific CD3 antigen, and its Fc region is selectively recognized by Fcγ type I/III receptor-positive immune cells. As a trifunctional...
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| Glavni autori: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499302/ https://ncbi.nlm.nih.gov/pubmed/22820509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.21003 |
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