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Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states.

The pheochromocytoma PC12 cell possesses specific cell surface receptors that bind nerve growth factor (NGF) with two different affinities. The rate of dissociation of NGF from the higher affinity receptor is slower than from the lower affinity receptor; this rate is reduced to essentially zero at l...

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Bibliographic Details
Main Authors: Landreth, G E, Shooter, E M
Format: Artigo
Language:Inglês
Published: 1980
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC349924/
https://ncbi.nlm.nih.gov/pubmed/6933521
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