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Chemical probes for higher-order structure in RNA.

Three chemical reactions can probe the secondary and tertiary interactions of RNA molecules in solution. Dimethyl sulfate monitors the N-7 of guanosines and senses tertiary interactions there, diethyl pyrocarbonate detects stacking of adenosines, and an alternate dimethyl sulfate reaction examines t...

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Main Authors: Peattie, D A, Gilbert, W
格式: Artigo
語言:Inglês
出版: 1980
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC349909/
https://ncbi.nlm.nih.gov/pubmed/6159633
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