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Elevated Hepatic Iron Activates NF-E2–Related Factor 2–Regulated Pathway in a Dietary Iron Overload Mouse Model

Hepatic iron overload has been associated classically with the genetic disorder hereditary hemochromatosis. More recently, it has become apparent that mild-to-moderate degrees of elevated hepatic iron stores observed in other liver diseases also have clinical relevance. The goal was to use a mouse m...

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Detalhes bibliográficos
Main Authors: Moon, Mi Sun, McDevitt, Emily I., Zhu, Junjia, Stanley, Bruce, Krzeminski, Jacek, Amin, Shantu, Aliaga, Cesar, Miller, Thomas G., Isom, Harriet C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499080/
https://ncbi.nlm.nih.gov/pubmed/22649188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs193
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