Controlled-release systemic delivery - a new concept in cancer chemoprevention

Many chemopreventive agents have encountered bioavailability issues in pre-clinical/clinical studies despite high oral doses. We report here a new concept utilizing polycaprolactone implants embedded with test compounds to obtain controlled systemic delivery, circumventing oral bioavailability issue...

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Bibliografske podrobnosti
Main Authors: Gupta, Ramesh C., Bansal, Shyam S., Aqil, Farrukh, Jeyabalan, Jeyaprakash, Cao, Pengxiao, Kausar, Hina, Russell, Gilandra K., Munagala, Radha, Ravoori, Srivani, Vadhanam, Manicka V.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2012
Teme:
Original Manuscript
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499062/
https://ncbi.nlm.nih.gov/pubmed/22696595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs209
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