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Genetic ablation of cyclooxygenase-2 in keratinocytes produces a cell-autonomous defect in tumor formation
Using a mouse skin tumor model, we reported previously that cyclooxygenase-2 (COX-2) deficiency reduced papilloma formation. However, this model did not differentiate between the effects of systemic COX-2-deficiency and keratinocyte-specific COX-2 deficiency on tumor formation. To determine whether...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499044/ https://ncbi.nlm.nih.gov/pubmed/22902545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs267 |
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