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The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16)

Hsp20 (heat-shock protein of 20 kDa; HspB6) is a cardioprotective agent which combats a number of pathophysiological processes in the heart, including hypertrophy, apoptosis and ischaemia/reperfusion injury. The cardioprotective actions of Hsp20 require its phosphorylation by PKA (cAMP-dependent pro...

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Detalhes bibliográficos
Main Authors: Edwards, Helen V., Scott, John D., Baillie, George S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498943/
https://ncbi.nlm.nih.gov/pubmed/22731613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20120570
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