Agonist versus antagonist binding to alpha-adrenergic receptors.

The binding properties of two alpha-adrenergic radioligands, [3H]epinephrine (an agonist) and [3H]dihydroergocryptine (an antagonist), were compared in two model systems--membranes derived from human platelets and membranes from rat liver. The platelet contains exclusively alpha 2 and the liver most...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hoffman, B B, Michel, T, Kilpatrick, D M, Lefkowitz, R J, Tolbert, M E, Gilman, H, Fain, J N
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1980
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349885/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6107908/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.4569
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