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Radiation-induced changes in microcirculation and interstitial fluid pressure affecting the delivery of macromolecules and nanotherapeutics to tumors

The immature, chaotic microvasculature of most solid tumors can present a significant impediment to blood-borne delivery, uneven distribution, and compromised penetration of macromolecular anticancer drugs and diagnostic agents from tumor microvessels across the interstitial space to cancer cells. T...

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Bibliografske podrobnosti
Main Authors: Multhoff, Gabriele, Vaupel, Peter
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498626/
https://ncbi.nlm.nih.gov/pubmed/23162794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00165
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