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Structure-function relationships of the outer membrane translocon Wza investigated by cryo-electron microscopy and mutagenesis

The outer membrane protein, Wza from E. coli K30, forms an octameric complex that is essential for capsular polysaccharide export. Homologs of Wza are widespread in gram-negative bacterial pathogens where capsules are critical virulence determinants. Wza is unusual in that it spans the outer membran...

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Bibliographic Details
Main Authors: Ford, Robert C., Brunkan-LaMontagne, Anne L., Collins, Richard F., Clarke, Bradley R., Harris, Robert, Naismith, James H., Whitfield, Chris
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498625/
https://ncbi.nlm.nih.gov/pubmed/19236919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2009.02.005
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