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“Fast Photochemical Oxidation of Proteins” (FPOP) and Mass Spectrometry Follow Sub-millisecond Protein Folding at the Amino-Acid Level

We report a study of sub-millisecond protein folding with amino-acid residue resolution achieved with a two-laser pump/probe experiment with analysis by mass spectrometry. The folding of a test protein, barstar, can be triggered by a laserinduced temperature jump (T jump) from ~0 °C to ~ room temper...

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Autors principals: Chen, Jiawei, Rempel, Don L., Gau, Brian C., Gross, Michael L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498593/
https://ncbi.nlm.nih.gov/pubmed/23075429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307606f
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