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Synthesis of Bridged Inside-Outside Bicyclic Ethers through Oxidative Transannular Cyclization Reactions

[Image: see text] The classical geometry of the 6-endo transition state for nucleophilic additions into oxocarbenium ions can be perturbed by incorporating the reactive groups into medium sized rings, leading to the formation of 2,6-trans-dialkyl tetrahydropyrans. The bicyclic products exhibit insid...

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Detalhes bibliográficos
Main Authors: Han, Xun, Floreancig, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498537/
https://ncbi.nlm.nih.gov/pubmed/22783950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol301720u
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