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Optimal noise reduction in 3D reconstructions of single particles using a volume-normalized filter

The high noise level found in single-particle electron cryo-microscopy (cryo-EM) image data presents a special challenge for three-dimensional (3D) reconstruction of the imaged molecules. The spectral signal-to-noise ratio (SSNR) and related Fourier shell correlation (FSC) functions are commonly use...

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Hlavní autoři: Sindelar, Charles V., Grigorieff, Nikolaus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498508/
https://ncbi.nlm.nih.gov/pubmed/22613568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.05.005
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