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Cardiac Protection by Preconditioning Is Generated via an Iron-Signal Created by Proteasomal Degradation of Iron Proteins

Ischemia associated injury of the myocardium is caused by oxidative damage during reperfusion. Myocardial protection by ischemic preconditioning (IPC) was shown to be mediated by a transient ‘iron-signal’ that leads to the accumulation of apoferritin and sequestration of reactive iron released durin...

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Detalhes bibliográficos
Main Authors: Bulvik, Baruch E., Berenshtein, Eduard, Meyron-Holtz, Esther G., Konijn, Abraham M., Chevion, Mordechai
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498359/
https://ncbi.nlm.nih.gov/pubmed/23155431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048947
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