Direct Angiotensin II Type 2 Receptor Stimulation Ameliorates Insulin Resistance in Type 2 Diabetes Mice with PPARγ Activation

OBJECTIVES: The role of angiotensin II type 2 (AT(2)) receptor stimulation in the pathogenesis of insulin resistance is still unclear. Therefore we examined the possibility that direct AT(2) receptor stimulation by compound 21 (C21) might contribute to possible insulin-sensitizing/anti-diabetic effe...

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Detalhes bibliográficos
Main Authors: Ohshima, Kousei, Mogi, Masaki, Jing, Fei, Iwanami, Jun, Tsukuda, Kana, Min, Li-Juan, Ogimoto, Akiyoshi, Dahlöf, Björn, Steckelings, Ulrike M., Unger, Tomas, Higaki, Jitsuo, Horiuchi, Masatsugu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498306/
https://ncbi.nlm.nih.gov/pubmed/23155382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048387
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