Antibodies from myasthenic patients that compete with cholinergic agents for binding to nicotinic receptors.
We have purified immunoglobulins from sera of myasthenic patients and have identified antibodies directed against the cholinergic ligand-binding site of the nicotinic acetylcholine receptor. In the serum of one patient analyzed in detail these antibodies belonged to the IgG3 class, and their effects...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1980
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933485/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.4326 |
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