Chronic Temporal Lobe Epilepsy Is Associated with Enhanced Alzheimer-Like Neuropathology in 3×Tg-AD Mice

The comorbidity between epilepsy and Alzheimer's disease (AD) is a topic of growing interest. Senile plaques and tauopathy are found in epileptic human temporal lobe structures, and individuals with AD have an increased incidence of spontaneous seizures. However, why and how epilepsy is associa...

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Detalhes bibliográficos
Main Authors: Yan, Xiao-Xin, Cai, Yan, Shelton, Jarod, Deng, Si-Hao, Luo, Xue-Gang, Oddo, Salvatore, LaFerla, Frank M., Cai, Huaibin, Rose, Gregory M., Patrylo, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498246/
https://ncbi.nlm.nih.gov/pubmed/23155407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048782
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