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Sickle-cell hemoglobin: fall in osmotic pressure upon deoxygenation.

Macromolecules such as hemoglobin exert both kinetic and matrix effects on osmotic pressure. The kinetic osmotic pressure of sickle-cell hemoglobin is lost upon deoxygenation at physiological erythrocyte concentrations. The non-kinetic or matrix component of osmotic pressure remains relatively uncha...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hargens, A R, Bowie, L J, Lent, D, Carreathers, S, Peters, R M, Hammel, H T, Scholander, P F
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1980
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349823/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933482/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.4310
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