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Switching on the macrophage-mediated suppressor mechanism by tumor cells to evade host immune surveillance.

The present study demonstrates a unique mechanism for tumor cell-induced immunosuppression. In the presence of a nonsuppressive dose of tumor cells, generation of cytotoxic T cells in the mixed lymphocyte culture (MLC) is completely suppressed by adding exogenous (peritoneal) macrophages (PM phi) af...

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Autori principali: Ting, C C, Rodrigues, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC349813/
https://ncbi.nlm.nih.gov/pubmed/6449005
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