Autoinactivation of the Stargazin–AMPA Receptor Complex: Subunit-Dependency and Independence from Physical Dissociation

Agonist responses and channel kinetics of native α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors are modulated by transmembrane accessory proteins. Stargazin, the prototypical accessory protein, decreases desensitization and increases agonist potency at AMPA receptors. Further...

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Bibliographic Details
Main Authors: Semenov, Artur, Möykkynen, Tommi, Coleman, Sarah K., Korpi, Esa R., Keinänen, Kari
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498123/
https://ncbi.nlm.nih.gov/pubmed/23166629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049282
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