Phenotypic evolution of cells resistant to bromodeoxyuridine.
Variants resistant to bromodeoxyuridine (BrdUrd) and deficient in thymidine kinase (ATP:thymidine 5'-phosphotransferase; EC 2.7.1.21) have been obtained from V79 Chinese hamster cells by a combination of spontaneous and drug-induced change. Initial mutations take place in wild-type populations as a...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1980
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933467/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.4206 |
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