Cloning, expression, purification, crystallization and X-ray analysis of inositol monophosphatase from Mus musculus and Homo sapiens

Inositol monophosphatase (IMPase) catalyses the hydrolysis of inositol monophosphate to inositol and is crucial in the phosphatidylinositol (PI) signalling pathway. Lithium, which is the drug of choice for bipolar disorder, inhibits IMPase at therapeutically relevant plasma concentrations. Both mous...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Singh, Nisha, Halliday, Amy C., Knight, Matthew, Lack, Nathan A., Lowe, Edward, Churchill, Grant C.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2012
Matèries:
Structural Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497969/
https://ncbi.nlm.nih.gov/pubmed/23027737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112035191
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars