Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking

Chronic intermittent access to alcohol leads to the escalation of alcohol intake, similar to binge drinking in humans. Converging lines of evidence suggest that impairment of medial prefrontal cortex (mPFC) cognitive function and overactivation of the central nucleus of the amygdala (CeA) are key fa...

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Autori principali: George, Olivier, Sanders, Chelsea, Freiling, John, Grigoryan, Edward, Vu, Shayla, Allen, Camryn D., Crawford, Elena, Mandyam, Chitra D., Koob, George F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497825/
https://ncbi.nlm.nih.gov/pubmed/23071333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116523109
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