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An Sp1/Sp3 Site in the Downstream Region of Varicella-Zoster Virus (VZV) oriS Influences Origin-Dependent DNA Replication and Flanking Gene Transcription and Is Important for VZV Replication In Vitro and in Human Skin

The distribution and orientation of origin-binding protein (OBP) sites are the main architectural contrasts between varicella-zoster virus (VZV) and herpes simplex virus (HSV) origins of DNA replication (oriS). One important difference is the absence of a downstream OBP site in VZV, raising the poss...

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Autors principals: Khalil, Mohamed I., Robinson, Makeda, Sommer, Marvin, Arvin, Ann, Hay, John, Ruyechan, William T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497629/
https://ncbi.nlm.nih.gov/pubmed/22933283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01538-12
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