Construction and Characterization of a Derivative of Neisseria gonorrhoeae Strain MS11 Devoid of All opa Genes

To better understand the role of Opa in gonococcal infections, we created and characterized a derivative of MS11 (MS11Δopa) that had the coding sequence for all 11 Opa proteins deleted. The MS11Δopa bacterium lost the ability to bind to purified lipooligosaccharide (LOS). While nonpiliated MS11Δopa...

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Bibliografiske detaljer
Main Authors: LeVan, Adriana, Zimmerman, Lindsey I., Mahle, Amanda C., Swanson, Karen V., DeShong, Philip, Park, Juhee, Edwards, Vonetta L., Song, Wenxia, Stein, Daniel C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497525/
https://ncbi.nlm.nih.gov/pubmed/23002223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00969-12
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