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Transient Deficiency of Dendritic Cells Results in Lack of a Merozoite Surface Protein 1-Specific CD4 T Cell Response during Peak Plasmodium chabaudi Blood-Stage Infection

Splenic dendritic cells are crucial for controlling the immune response to malaria by initiating a CD4 gamma interferon (IFN-γ) response early in a blood-stage infection, which contributes to parasite clearance as well as to acute-stage immunopathology. CD8(−) CD11c(high) dendritic cells have been d...

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Detalhes bibliográficos
Main Authors: Sponaas, Anne-Marit, Belyaev, Nikolai, Falck-Hansen, Mika, Potocnik, Alexandre, Langhorne, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497445/
https://ncbi.nlm.nih.gov/pubmed/23006847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00820-12
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