Progressive Cross-Reactivity in IgE Responses: an Explanation for the Slow Development of Human Immunity to Schistosomiasis?

People in regions of Schistosoma mansoni endemicity slowly acquire immunity, but why this takes years to develop is still not clear. It has been associated with increases in parasite-specific IgE, induced, some investigators propose, to antigens exposed during the death of adult worms. These antigen...

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Bibliografiska uppgifter
Huvudupphovsmän: Fitzsimmons, Colin M., Jones, Frances M., Pinot de Moira, Angela, Protasio, Anna V., Khalife, Jamal, Dickinson, Harriet A., Tukahebwa, Edridah M., Dunne, David W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2012
Ämnen:
Fungal and Parasitic Infections
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497412/
https://ncbi.nlm.nih.gov/pubmed/23006852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00641-12
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