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Enterotoxigenic Escherichia coli Prevents Host NF-κB Activation by Targeting IκBα Polyubiquitination

The NF-κB pathway regulates innate immune responses to infection. NF-κB is activated after pathogen-associated molecular patterns are detected, leading to the induction of proinflammatory host responses. As a countermeasure, bacterial pathogens have evolved mechanisms to subvert NF-κB signaling. Ent...

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Bibliografiset tiedot
Päätekijät: Wang, Xiaogang, Hardwidge, Philip R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497408/
https://ncbi.nlm.nih.gov/pubmed/23027537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00809-12
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