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Carboxypeptidase A mechanisms.

The mode of binding of a ketonic substrate, which is an analogue of esters in which the O of the scissile bond is replaced by CH2, to carboxypeptidase A is similar to that of Gly-Tyr. The site is S'1, with the side chain in the pocket of the enzyme, the carboxylate salt-linked to Arg-145, and the ca...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autor: Lipscomb, W N
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1980
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349729/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933442/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.3875
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