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Stability of Colistimethate Sodium in Aqueous Solution
Colistimethate sodium, increasingly used to treat multidrug-resistant Gram-negative infections, spontaneously hydrolyzes to form colistin A (polymyxin E1) and B (polymyxin E2/B) when mixed with water. High levels of these active breakdown products at the time of administration have been associated w...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497204/ https://ncbi.nlm.nih.gov/pubmed/23070159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01079-12 |
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