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Targeted Delivery of EV peptide to Tumor Cell Cytoplasm Using Lipid Coated Calcium Carbonate Nanoparticles
Intracellular-acting peptide drugs are effective for inhibiting cytoplasmic protein targets, yet face challenges with penetrating the cancer cell membrane. We have developed a lipid nanoparticle formulation that utilizes a pH-sensitive calcium carbonate complexation mechanism to enable the targeted...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496799/ https://ncbi.nlm.nih.gov/pubmed/22796364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2012.07.011 |
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