Bone Regeneration with Low Dose BMP-2 Amplified by Biomimetic Supramolecular Nanofibers within Collagen Scaffolds

Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive cytokine that plays a critical role during bone regeneration and repair. In the extracellular environment, sulfated polysaccharides anchored covalently to glycoproteins such as syndecan and also non-covalently to fibronectin fibers have...

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Autors principals: Lee, Sungsoo S., Huang, Brian J., Kaltz, Stuart R., Sur, Shantanu, Newcomb, Christina J., Stock, Stuart R., Shah, Ramille N., Stupp, Samuel I.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496771/
https://ncbi.nlm.nih.gov/pubmed/23099062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.10.005
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