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Penalized Nonlinear Least Squares Estimation of Time-Varying Parameters in Ordinary Differential Equations
Ordinary differential equations (ODEs) are widely used in biomedical research and other scientific areas to model complex dynamic systems. It is an important statistical problem to estimate parameters in ODEs from noisy observations. In this article we propose a method for estimating the time-varyin...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496750/ https://ncbi.nlm.nih.gov/pubmed/23155351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1198/jcgs.2011.10021 |
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