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Inherited gastrointestinal stromal tumor syndromes: mutations, clinical features, and therapeutic implications
The discovery of underlying molecular genetic abnormalities in gastrointestinal stromal tumors (GISTs) such as activating mutations in the tyrosine kinase genes, KIT and platelet derived growth factor receptor-alpha (PDGFRA), has led to remarkable clinical advances in treatment. Small molecule inhib...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496697/ https://ncbi.nlm.nih.gov/pubmed/23036227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-2-16 |
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