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The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer
Leukotrienes (LTs) are lipid-signaling molecules derived from arachidonic acid (AA) that initiate and amplify inflammation. To initiate LT formation, the 5-lipoxygenase (5-LO) enzyme translocates to nuclear membranes, where it associates with its scaffold protein, 5-lipoxygenase–activating protein (...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Cell Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496618/ https://ncbi.nlm.nih.gov/pubmed/23015755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-06-0489 |
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