Positron emission tomography imaging of tumor angiogenesis and monitoring of antiangiogenic efficacy using the novel tetrameric peptide probe (64)Cu-cyclam-RAFT-c(-RGDfK-)(4)

(64)Cu-cyclam-RAFT-c(-RGDfK-)(4) is a novel multimeric positron emission tomography (PET) probe for α(V)β(3) integrin imaging. Its uptake and α(V)β(3) expression in tumors showed a linear correlation. Since α(V)β(3) integrin is strongly expressed on activated endothelial cells during angiogenesis, w...

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Detalhes bibliográficos
Main Authors: Jin, Zhao-Hui, Furukawa, Takako, Claron, Michael, Boturyn, Didier, Coll, Jean-Luc, Fukumura, Toshimitsu, Fujibayashi, Yasuhisa, Dumy, Pascal, Saga, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496517/
https://ncbi.nlm.nih.gov/pubmed/22644563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-012-9281-1
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