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Regulation of the stability of poly(I)xpoly(C)-induced human fibroblast interferon mRNA: selective inactivation of interferon mRNA and lack of involvement of 2',5'-oligo(A) synthetase activation during the shutoff of interferon production.

The inactivation of interferon mRNA during the shutoff phase of interferon production in poly(I)xpoly(C)-induced human fibroblast cultures is selective. We have determined that the shutoff of interferon production, which takes place from 3 to 8 hr after the beginning of induction, is not associated...

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Autori principali: Sehgal, P B, Gupta, S L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1980
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC349642/
https://ncbi.nlm.nih.gov/pubmed/6158049
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