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Rescue of Synaptic Plasticity and Spatial Learning Deficits in the Hippocampus of Homer1 Knockout Mice by Recombinant Adeno-Associated Viral Gene Delivery of Homer1c
Homer1 belongs to a family of scaffolding proteins that interact with various post-synaptic density proteins including group I metabotropic glutamate receptors (mGluR1/5). Previous research in our laboratory implicates the Homer1c isoform in spatial learning. Homer1 knockout mice (H1-KO) display cog...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496399/ https://ncbi.nlm.nih.gov/pubmed/21945599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2011.08.009 |
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