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Enzymatic analysis of α-ketoglutaramate—A biomarker for hyperammonemia

Two enzymatic assays were developed for the analysis of α-ketoglutaramate (KGM)—an important biomarker of hepatic encephalopathy and other hyperammonemic diseases. In both procedures, KGM is first converted to α-ketoglutarate (KTG) via a reaction catalyzed by ω-amidase (AMD). In the first procedure,...

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Autores principales: Halámková, Lenka, Mailloux, Shay, Halámek, Jan, Cooper, Arthur J.L., Katz, Evgeny
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496271/
https://ncbi.nlm.nih.gov/pubmed/23141304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.talanta.2012.08.022
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