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Acute promyelocytic leukaemia and acquired α-2-plasmin inhibitor deficiency: a retrospective look at the use of epsilon-aminocaproic acid (Amicar) in 30 patients

Bleeding diathesis and a hyper-fibrinolytic state often accompany a diagnosis of Acute Promyelocytic Leukaemia (APML). This complication can have grave effects if not successfully treated, with a 10–20% incidence of haemorrhagic death. We hypothesized that α-2-antiplasmin levels would correlate with...

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Autori principali: Wassenaar, T., Black, J., Kahl, B., Schwartz, B., Longo, W., Mosher, D., Williams, E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496178/
https://ncbi.nlm.nih.gov/pubmed/18613223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hon.867
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