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Innovative use of a bacterial enzyme involved in sialic acid degradation to initiate sialic acid biosynthesis in glycoengineered insect cells

The baculovirus/insect cell system is widely used for recombinant protein production, but it is suboptimal for recombinant glycoprotein production because it does not provide sialylation, which is an essential feature of many glycoprotein biologics. This problem has been addressed by metabolic engin...

詳細記述

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書誌詳細
主要な著者: Geisler, Christoph, Jarvis, Donald L.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496044/
https://ncbi.nlm.nih.gov/pubmed/23022569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymben.2012.08.005
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