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Rapamycin Protects against Myocardial Ischemia-Reperfusion Injury through JAK2-STAT3 Signaling Pathway

Rapamycin (Sirolimus®) is used to prevent rejection of transplanted organs and coronary restenosis. We reported that rapamycin induced cardioprotection against ischemia-reperfusion (I/R) injury through opening of mitochondrial K(ATP) channels. However, signaling mechanisms in rapamycin-induced cardi...

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Bibliographische Detailangaben
Hauptverfasser: Das, Anindita, Salloum, Fadi N., Durrant, David, Ockaili, Ramzi, Kukreja, Rakesh C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496042/
https://ncbi.nlm.nih.gov/pubmed/22999860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.09.007
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